🌈 MDMA Supplement & Recovery Guide
For safer, smoother, and more restorative experiences
⚠️ Disclaimer: This guide is for educational and harm-reduction purposes only. It is not medical advice. Always consult a licensed healthcare provider before taking any supplement or combining substances. MDMA carries risks — test your materials and use responsibly. All of the supplements listed here can be found at a pharmacy or online. Check reviews to pick a reliable brand.
⚙️ Pre-Roll Support
🌿 Regular Routine
4h before: 2g Ginger — reduce nausea
3h before: 500mg ALCAR, 500mg Vitamin C — antioxidant & energy support
2h before: Hydrate & rest
1h before: 2g Ginger, optional 100mg Magnesium — relax muscles
With MDMA: 300mg ALA, 500mg Vitamin C — counter oxidative stress
+1h: 300mg ALA, 500mg ALCAR — neuroprotection
+2h: 300mg ALA, optional 100mg Magnesium
+3–7h: 300mg ALA each hour
+5h: +500mg ALCAR
Before bed: Melatonin — sleep & serotonin balance
🧭 Minimal Routine
13h before: 800 IU Vitamin E — antioxidant
7h before: 200–600 mg CoQ10 — mitochondrial support
3h before: 1000 mg ALCAR — neuroprotection
Do not exceed 2500 mg ALCAR, 3600 mg CoQ10, or 1600 IU Vitamin E per day.
🌅 Post-Roll Recovery (12–72 h after)
1️⃣ Neurochemical & Mood Recovery
🦃 L-Tryptophan / Protein foods (turkey, milk, eggs, oats) — natural serotonin precursor; take with carbs
🧠 Omega-3s (1000–2000 mg EPA/DHA) — restore cell membranes
🌿 Curcumin 500 mg — anti-inflammatory; take with food + black pepper
☀️ Vitamin D3 1000–2000 IU — mood & immune support
🫐 Antioxidant foods (berries, greens, green tea) — reduce oxidative stress
2️⃣ Sleep & Nervous-System Reset
😴 Melatonin 0.5–3 mg — reset circadian rhythm
🌼 L-Theanine 200 mg — calm focus
💧 Magnesium 200–400 mg (glycinate / citrate) — muscle & nerve relaxation
3️⃣ Liver & Mitochondrial Recovery
💊 N-Acetyl-Cysteine (NAC) 600–1200 mg — boosts glutathione & detox (2–3 days)
⚙️ ALA + ALCAR (300 + 500 mg twice daily) — mitochondrial support
💧 Hydration + Electrolytes — replace fluids, avoid overhydration
☀️ Sunlight + Gentle Exercise — natural serotonin & BDNF boost
⚠️ About 5-HTP
Not recommended within 24 h of MDMA.
After 24–48 h, some users report mild benefit (50–100 mg + Vitamin B6) but results vary.
Tryptophan-rich foods are safer & self-regulated by the body.
🧩 Example Day-After Plan
Morning: Hydrate; breakfast with eggs/oats/berries; Omega-3s + Vitamin C
Afternoon: NAC 600 mg; sunlight walk; Curcumin 500 mg
Evening: Magnesium 200 mg; L-Theanine 200 mg; Melatonin 1 mg before bed
❤️ General Notes
- Sleep is the best recovery tool.
- Avoid alcohol, cannabis, or stimulants post-roll.
- Eat balanced meals with protein, healthy fats, and complex carbs.
- Test your substance (Marquis / Ehrlich kits).
- Space rolls at least 2–3 months apart for serotonin recovery.
📚 Source: Adapted from RollSafe.org and peer-reviewed research on MDMA neuroprotection & recovery.
