🌈 MDMA Supplement & Recovery Guide

For safer, smoother, and more restorative experiences

Individuals who followed this protocol have reported significantly reduced side-effects the next day and fast recovery. At first - especially if you have never done something like this before - this may seem like a lot to do, but it makes a difference.

Other considerations: Hydration with electrolytes is also an important thing to add to any MDMA protocol. Too much water w/o electrolytes and cause hyponatremia (low blood sodium) which is also bad.

To additionally manage a sore throat or tongue, also consider chewing gum, hard candy, or if you’re real fancy a pacifier :)

For more information about MDMA - read our blog post here.

⚠️ Disclaimer: This guide is for educational and harm-reduction purposes only. It is not medical advice. Always consult a licensed healthcare provider before taking any supplement or combining substances. MDMA carries risks — test your materials with a test kit and fentanyl strips and use responsibly. All of the supplements listed here can be found at a pharmacy or online. Check reviews to pick a reliable brand.

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⚙️ Pre-Roll Support

🌿 Regular Routine

4h before: 2g Ginger — reduce nausea
3h before: 500mg ALCAR, 500mg Vitamin C — antioxidant & energy support
2h before: Hydrate & rest
1h before: 2g Ginger, optional 100mg Magnesium — relax muscles
With MDMA: 300mg ALA, 500mg Vitamin C — counter oxidative stress
+1h: 300mg ALA, 500mg ALCAR — neuroprotection
+2h: 300mg ALA, optional 100mg Magnesium
+3–7h: 300mg ALA each hour
+5h: +500mg ALCAR
Before bed: Melatonin — sleep & serotonin balance

🧭 Minimal Routine

13h before: 800 IU Vitamin E — antioxidant
7h before: 200–600 mg CoQ10 — mitochondrial support
3h before: 1000 mg ALCAR — neuroprotection
Do not exceed 2500 mg ALCAR, 3600 mg CoQ10, or 1600 IU Vitamin E per day.

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🌅 Post-Roll Recovery (12–72 h after)

1️⃣ Neurochemical & Mood Recovery

🦃 L-Tryptophan / Protein foods (turkey, milk, eggs, oats) — natural serotonin precursor; take with carbs
🧠 Omega-3s (1000–2000 mg EPA/DHA) — restore cell membranes
🌿 Curcumin 500 mg — anti-inflammatory; take with food + black pepper
☀️ Vitamin D3 1000–2000 IU — mood & immune support
🫐 Antioxidant foods (berries, greens, green tea) — reduce oxidative stress

2️⃣ Sleep & Nervous-System Reset

😴 Melatonin 0.5–3 mg — reset circadian rhythm
🌼 L-Theanine 200 mg — calm focus
💧 Magnesium 200–400 mg (glycinate / citrate) — muscle & nerve relaxation

3️⃣ Liver & Mitochondrial Recovery

💊 N-Acetyl-Cysteine (NAC) 600–1200 mg — boosts glutathione & detox (2–3 days)
⚙️ ALA + ALCAR (300 + 500 mg twice daily) — mitochondrial support
💧 Hydration + Electrolytes — replace fluids, avoid overhydration
☀️ Sunlight + Gentle Exercise — natural serotonin & BDNF boost

⚠️ About 5-HTP

Not recommended within 24 h of MDMA.
After 24–48 h, some users report mild benefit (50–100 mg + Vitamin B6) but results vary.
Tryptophan-rich foods are safer & self-regulated by the body.

🧩 Example Day-After Plan

Morning: Hydrate; breakfast with eggs/oats/berries; Omega-3s + Vitamin C
Afternoon: NAC 600 mg; sunlight walk; Curcumin 500 mg
Evening: Magnesium 200 mg; L-Theanine 200 mg; Melatonin 1 mg before bed

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❤️ General Notes

• Sleep is the best recovery tool.
• Avoid alcohol, cannabis, or stimulants post-roll.
• Eat balanced meals with protein, healthy fats, and complex carbs.
• Test your substance (Marquis / Ehrlich kits).
• Space rolls at least 2–3 months apart for serotonin recovery.

📚 Source: Adapted from RollSafe.org and peer-reviewed research on MDMA neuroprotection & recovery.

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An alternative single stop solution is raverx.com which provides pre-packaged vitamins for pre-, mid-, and post roll.